Microvascular Obstruction and the No-Reflow Phenomenon After Percutaneous Coronary Intervention

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Microvascular obstruction and the no-reflow phenomenon after percutaneous coronary intervention.

Case presentation A: A 50-year-old diabetic man presented to the hospital after 8 hours of continuous chest pain. Because of acute myocardial infarction of the anterior wall, he underwent direct stenting to an occlusion in the left anterior descending coronary artery. Despite revascularization, suboptimal coronary flow was achieved, and he subsequently developed heart failure. Case presentation...

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Predicting the no-reflow phenomenon following successful percutaneous coronary intervention.

In the setting of acute myocardial infarction, early and adequate reopening of an infarct-related artery is not necessarily followed by a complete restoration of myocardial perfusion. This condition is usually defined as 'no-reflow'. The pathophysiology of no-reflow is multifactorial since extravascular compression, microvascular vasoconstriction, embolization during percutaneous coronary inter...

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Primary percutaneous coronary intervention: devices to prevent no-reflow phenomenon

Primary percutaneous coronary intervention, where available, has become the therapy of choice in myocardial reperfusion during ST-elevation myocardial infarction. However, in a significant proportion of patients, owing to a high thrombus burden, myocardial perfusion is not fully achieved in the epicardial vessel. This phenomenon has been attributed predominantly to the distal embolization of th...

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Incidence and treatment of 'no-reflow' after percutaneous coronary intervention.

BACKGROUND Profound reduction in antegrade epicardial coronary flow with concomitant ischemia is seen occasionally during percutaneous coronary intervention despite the absence of evident vessel dissection, obstruction, or distal vessel embolic cutoff. In a prior small series of cases, this "no-reflow" phenomenon appeared to be promptly reversed by the intra-coronary administration of verapamil...

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hsCRP and ET-1 expressions in patients with no-reflow phenomenon after Percutaneous Coronary Intervention

OBJECTIVE To explore hsCRP and ET-1 expressions in patients with no-reflow phenomenon after percutaneous coronary intervention (PCI). METHODS A total of 136 patients with single coronary artery disease receiving PCI were divided into a reflow group and a no-reflow group to compare the level use of ET-1 alone with combined level of ET-1 and hs-CRP in PCI regarding sensitivity, specificity, pos...

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ژورنال

عنوان ژورنال: Circulation

سال: 2008

ISSN: 0009-7322,1524-4539

DOI: 10.1161/circulationaha.107.742312